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Injectable Line \\ Oxymetholone

Oxymetholone

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Created in 1960 in Mexico, but was first launched on the market in the same year by the American company Syntex under the trademark "Anadrol-50".

Oxymetholone profile

Chemical name: 17 beta-hydroxy-2-hydroxymethylene-17 alpha-methyl-5 alpha-androstan-3-one

Formula: C21H32O3

Molecular weight: 332.482

Release year: 1960

Anabolic activity index: 320 % of testosterone

Androgenic activity index: 45 % of testosterone

Aromatization: no, but estrogenic itself

Hepatoxicity: yes

Route of administration: oral, injectable

Effective oxymetholone dosage: 250-350 mg/week

Active half-life: 8-9 hours

Detection time: up to 8 weeks

Benefits:

Significant increase in muscle mass;

Significant increase in strength;

SHBG level lowering;

Increase of hemoglobin level.

Possible oxymetholone side effects:

High load on the liver;

Pronounced estrogenic effects (water retention, gynecomastia, high blood pressure);

Androgenic side effects typical for DHT (alopecia, acne, enlarged prostate, etc.);

Adverse effect on lipid profile;

Significant suppression of HPTA.

Virilization in women

Oxymetholone (also known as anapolon and anadrol) is a very drastic synthetic steroid, 17-alpha-alkylated modification of dihydrotestosterone. It was developed for the treatment of osteoporosis and anaemia, as well as to stimulate muscle gain in malnourished and debilitated patients. Oxymetholone has been approved by the American Food and Drug Administration (FDA) for use in humans. Later there where created non-steroidal drugs that effectively could treat anaemia and osteoporosis; because of this anapolon lost his popularity and by 1993 Syntex decided to cease the production of the drug, as well as other manufacturers did.

By its performance parameters oxymetholone is most similar to methandienone.  As with methandienone, it provokes not only active muscle bulking, but also a significant increase in power performance. A newbie can grow by 9-15 kg within 6 weeks while taking oxymetholone. However, a large part of the gained weight is because of water retention in the body, which can lead to high blood pressure on cycle.  Due to the water retention, a significant rollback phenomenon is typical for the drug.

Features of Anadrol

Anapolon with the active chemical substance - oxymetholone, considered one of the most effective, oral anabolic steroids to date, and at the same time, its side effects on the body as well, making it the leading in the list of harmful steroids.

Anadrol will allow in a short time to pump up the "exaggerated" the muscle, on average 5-7 kg of muscle in 2 weeks. This super anabolic effects of Anapolon, due to the strong accumulation of water in the body, so that there is a strong, muscular hypertrophy, the musculature becomes massive, puffy look. That is, the reception will give you a rough Anadrol muscle mass that needs to be further developed, the relief.

Accumulation of water provide you with the lubrication of joints, making your workout in the gym will be painless, besides water retention is one of the forces of growth factors. Excessive accumulation of water in the body is a negative consequence of taking anabolic steroids, so to avoid a large water retention, take Nolvadex and Proviron, while receiving these drugs, does not reduce the growth of gross and massive musculature.

During the reception of Anadrol, athlete can observe a significant increase in red blood cells, which means better blood supply of oxygen, and as a consequence of increased muscle endurance athlete is experiencing an unprecedented feeling of "pampas" of the pump. About overtraining muscle with a drug can be forgotten, as oxymetholone promotes early recovery of the body after exercise, you may find that you're a robot, and can train endlessly.

Anadrol does not provide a qualitative growth of muscle mass, only the quantitative, so builders prefer to use the drug in the offseason, but can be successfully used it and to prepare for the competition, using the last week of antiestrogens and diuretics, to display the excess water from the orgasm.

Thanks to its ability to influence the level of hemoglobin and to increase the blood volume in the body, oxymetholone may cause an extremely strong pumping effect by athletes, which consequently complicates the training process, because muscles get sore almost immediately after the first heavy set.

Anadrol Side Effects

Simultaneous reception Anadrol and testosterone in high doses may cause violent aggression.

When muscle mass set, the reception Anadrol, usually accompanied by a high-calorie food, and it often leads to increased levels of blood cholesterol, as well as to the high level of low density lipoproteins.

Anadrol has a depressing effect over the hypothalamus, as a consequence of its own testosterone produced by the body stops, due to low productivity, or even refusal to release of gonadotropin. Therefore, always use drugs that stimulate the production of testosterone by the body, such as Clomid and HCG (human chorionic gonadotropin) during the steroid cycle, otherwise, advanced cases, original, strong attraction to the female sex during the course may fall after the abolition of all steroids.

Anadrol is contraindicated to use in women, because entails a strong androgenic, irreversible action. Women who have used oxymetholone observed at the phenomenon of masculinization, ie, increased hair growth on the body and the face, loss of hair on the head, deepening of the voice, enlargement of the clitoris, increased libido. But everywhere there are exceptions to the rule, if a girl wants, no matter what to try the strongest oral steroid Anadrol, the dosage should be minimal - 25 mg (half tablet) for 2-4 days, with a break in combination with "soft" steroid anabolic effects in injection form, Primobolan Depot or Durabolin.

Anapolon is a derivative of dihydrotestosterone, which gives it a chemical structure that does not aromatize. Despite the fact that anapolon does not directly convert to estradiol, it itself has pronounced estrogenic properties. It should be remembered that because of this peculiarity only antiestrogens would be able to combat with estrogenic side effects, but not aromatase inhibitors, because aromatase is not involved into the process.  Aromatase inhibitors would be completely useless here.

Some suggest that oxymetholone`s estrogenic activity relates to the progestogenic one, like with nandrolones. Side effects may be similar. However, medical studies have shown that Anapolon does not possess any progestogenic activity.

When taking oxymetholone severe acne and hair loss as well as prostate problems and irritability are possible. 5-alpha-reductase inhibitors will be useless here in terms of blocking side effects, as oxymetholone does not convert to DHT, it itself is DHT derivative.   

If any of these side effects comes into the picture, only dose reduction or drug withdrawal will be useful.

Anadrol quickly suppresses hypothalamic-pituitary-testicular axis (HPTA) and endogenous testosterone, hence post-cycle therapy based on antiestrogens is required.

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